"First, let's get one thing perfectly clear about sulfites in wine: This is a natural process that's been used by winemakers for a couple of thousand years, with the benign purpose of keeping your wine from spoiling before you can drink it.
"With the limited exception of sulfite-sensitive asthmatics, who must avoid sausages, pickles and many other good things in addition to wine, most of us needn't worry about it. If you get a headache or a stuffy nose after drinking wine, you may be allergic to something - very likely the histamines in some red wines, or in the case of hangovers, simple over-indulgence. But it's not the sulfites.
"But the scary warning label, added to wine by government fiat as recently as the 1990s, prompts reactions that range from wary to hysterical among some wine consumers...."
I regularly hear people say they avoid red wines, or certain kinds of red wines, because "they give me a headache." I don't really know what to make of this complaint. I suspect a substantial number are the result simplyi of overindulgence, as Robin says above. The alcohol in the wines, folks, will give you a headache if you drink enough of it. You don't need mysterious evil added chemicals. And some red wines contain a lot of alcohol -- 16% or more in some cases!